Bone and Mineral Metabolism

Although bones are normally thought structures that fracture when one falls, bone is actually a very active metabolic organ. It is vital in the regulation of calcium and phosphate metabolism, magnesium storage, and in buffering metabolic acido-sis. Bone and mineral metabolism and some of their disorders are presented in this article. It is vital in the regulation of calcium and phosphate metabolism, magnesium storage, and in buffering metabolic acido-sis.

Derangements of calcium, magnesium, and phosphate are associated with increased morbidity and mortality. These minerals have vital roles in the cellular physiology of the neuromuscular and cardiovascular systems.

Maturation of mammalian bone minerals-A new method for determining bone metabolism

The present report begins by comparing data on bone mineralization communicated in the literature to date with the authors' own previously published concept of the "three-phase model". The age-dependent accumulation of minerals in the femurs of Wistar rats was also chemically-analytically investigated. The results suggest that the mineral first formed is octacalcium phosphate. It is followed by sodium- and magnesium-containing phases. Maturation of octacalcium phosphate only occurs after this; it is converted into a highly carbon-deficient hydroxyapatite. During this conversion the molar Ca/P ratio rises from 1.33 to 2. However, the final value of 2 is not fully attained: this is attributable to the "turnover" activity of bone-metabolic processes.

Osteoporosis protective measures of nutrition and exercise:

Postural correction and strengthening exercises should be prescribed--and we must be as particular about these prescriptions as we are about those for drugs. An ideal exercise program for an older osteoporotic patient can be easy to understand, simple to carry out, and safe. Add a calcium supplement if the dietary intake is inadequate. However, calcium alone can only prevent further bone reduction. It must be combined with exercise ideally before menopause--to prevent bone loss and build up a "reserve" of bone mass.

Endocrinology and Metabolism: Open Access is a peer reviewed journal which focuses on the publication of current research and developments on the endocrine glands and its secretions with their coordination with metabolism and reproduction.

Endocrinology and Metabolism: Open Access Journal is using Editorial Tracking System to maintain quality and transparency to the author in the peer-review process. Review processing will be performed by the editorial board members of the Journal Endocrinology and Metabolism: Open Access or by Reviewers (outside experts in the field). Two independent reviewer’s approval (Minimum reviewer’s approval) followed by editor approval is obligatory for acceptance of any manuscript excluding an editorial.

Journal is now accepting manuscripts for volume 5 for year 2021. We publish minimum of 5 and maximum of 20 articles per issue every month. Submissions to our journal are given high priority during the process.

Submit your manuscript at:

https://www.imedpub.com/submissions/endocrinology-metabolism-open-access.html

You may also send the manuscript as an attachment to mail endometabol@emedscholar.com

Media Contact
Eliza Grace
Associate Managing Editor
Endocrinology and Metabolism: Open Access
E-Mail: endometabol@emedscholar.com